Psoriasis - the treatment of the first phase of psoriasis

What is psoriasis? Otherwise, it is known as psoriasis. This is a complex infectious-inflammatory process localized mainly in the tissues of the dermis (hands, back, etc.). It is considered a kind of dermatosis. It is characterized by the formation of red elevations on the skin (wheals) that eventually merge together, forming large lesions.

The incidence of the disease varies from 0.1 to 3%. The average incidence rate - 2.5% of the total population of the planet. The disease causes process the more exposed the people who live in the civilized States. For sure on the described pathology unknown nothing: etiology, pathogenesis, all these questions that there is not a single answer. There are only guesses and theories. What you should know about the disease of psoriasis?

Psoriasis - the causes of the training

The above mentioned pathology differs multifactoriality and polyethiologic. In practice, this means that the causes of psoriasis are many, the role played by various factors. The immediate reason is the reduction of the life cycle of epidermal cells: normal structure of the dermis "live" a month and a half, while in the scaly lichen, this period is reduced to a few days.

In the end, the rate of cell death is greater than the intensity of their updates. The scales of the epidermis are shed, forming big growth and cause irritation.

1. Disorders of the metabolism. According to the first theory of psoriasis (picture symptoms and treatment in adults are presented in this article) arises as a reaction to a metabolism slower. It should be noted that many patients expressed increased concentrations of cholesterol, indicating changes in lipid metabolism. In this context, the disease can be considered as a "cholesteric diathesis". The imbalance observed in the structure of the vitamin a-metabolism and mineral: the typical clinical picture includes the lack of vitamins, And the vitamin C content increases. Some may play a role hypothyroidism (insufficient thyroid function), the lack of sex hormones;
2. The genetic factor. Considered to be one of the reasons for the formation of the disease. Inherited not psoriasis photo symptoms and treatment in adults are presented later), and a predisposition to it. Geneticists installed if the old uplink was a person who suffer from the scaly ringworm, the risk in the offspring rises to 25%. When she is sick both parents, with a probability of 75% of patients and a child. Demonstrated 70% of patients with a dermatologist with a verified diagnosis a positive family history;
3. The autoimmune theory. Today it is considered the most authoritative and academic. The hypothesis States that at some point the immune system of the patient fails, the result of which the protection system is healthy cells for dangerous "intruders". Started active development of leukocytes and other cells of the immune system that destroy the structure of the dermis. The Foundation of the pathology is the presence of a source of chronic infection: we can speak of diseases of the throat, nasopharynx, etc. With a current blood or lymph pathogenic flora is transported to the skin, forming new lesions. If you believe that the theories that we're talking about a delay in the immune response;
4. The infectious hypothesis. Until recently it was considered as the most reliable and irrefutable. Its essence lies in the idea of the tiles as contagious infectious disease. The negligence is "imputed" and staphylococci, and streptococci, and spirochetes, as a result, with the direct contact of the psoriasis is not transmitted from person to person that the evidence in favor of non-infectious origin.

All the theories have presented a grain of truth. This problem is considered as a complex, polietiologic disease. One can also speak of a series of factors caused. Are the triggers (cause manifestation or a relapse), it helps in the healing of psoriasis:

• Climate change;
• Psoriasis frequent stress. It is assumed that the role in the development of the disease has a hormonal imbalance: active cortisol, epinephrine, and norepinephrine;
• The abuse of alcohol;
• The medication. Mainly anti-inflammatory, vitamins, cytostatics;
• Hypothermia;
• Injury of the epidermis.

Causes of the disease are numerous. In order to understand them only attendees specialist.

Classification

To classify the disease it is possible for four reasons: the shape, the nature of the current, scene, and location.

Form:

1. Pustular form;
2. Not the vascular form.

Current patterns are:

• Generalized type (pustular psoriasis). Psoriasis is rare, not more than 1% of the cases. It is characterized by a rapid, aggressive course. In a short period of time in the skin appear red spots, confluent into a single lesion. The most frequent location of the pathological process: in the groin, under the arms, in the field of the anatomy of the curves of the limbs;
• Exudative form. Developed as secondary lesions in patients with disorders of the thyroid gland, with diabetes. This form is characterized by the exudation of liquid components of the blood with the formation of the surface of the wound. When the removal of the layer of the skin exposing the affected area of the skin with the release of large amounts of liquid;
• Plate in the form of type. The most common form of the disease. Found in 85% of cases. The "classic" form of psoriasis begins with the appearance of the dermis of one or more red papules covered with dead skin cells. In the future several months or years plot confused. Location: in your hands, the curves of the limbs, the scalp, etc.;
• The atypical form. Occurs only on rare occasions. It is characterized by atypical localization of papules;
• The form of a tear. It received its name by the shape of the plates.

Localization distinguished:

• In the hands and feet;
• In the body;
• In the face;
• In the head;
• In nails.

In isolation, these forms do not occur.

• The initial phase. The disease is manifested with the formation of a small "grain" or a slick rounded, red or purple. Legs bluish. Surface papules covered with silvery scales remove, that are poorly connected to the dermis and can be easily removed mechanical impact to all of these psoriasis;
• Stage of progression. The clinical picture worsens. Format fresh, papules, over time all the red dots merge together, forming conglomerates. The skin in the affected areas is red, forms erythematous halos. Unlike the plates in a first phase, the progression of the plaque do not have clear boundaries and gentle way;
• Phase stationary. Advanced stage of scaly lichen. In this stage, the formation of new lesions ceased, the old papules to disappear and cease to increase in volume. Extensive growth stops.

Sometimes isolated and regressing stage, when the platelets decrease in size.

Pathognomonic recurrent, cyclic course. Each new cycle is characterized by four stages.

Symptoms

The clinical picture is typical. The symptoms of "classic" psoriasis include:

• The formation of the papules is psoriasis. The diameter of the redness of 1 mm to 3 cm. In typical cases, the process is localized to the hands, scalp, back;
• Horny thickening of the skin. The dermis in the affected areas is difficult, are formed similar to corn growth. In remission when the redness goes, Horny growths persist;
• A feeling of itching, burning of the affected areas of the epidermis. Because of the infiltrative process of the receptors of the skin itching. There is a reflex desire to scratch psoriatic plaques;
• The development of cracks in the skin.

With the defeat of nails observed:

• Plot the ulceration of the nail plate;
• Change the color of the nails on the type of fungi;
• Disorders of the structure of the nail.

Psoriasis, a systemic disease during which is celebrated the total defeat of all the systems of the body. In the advanced stages can be seen, and generalized manifestations of the disease:

• Weakness;
• Hypo - or hyperthermia, due to the immune reaction;
• Disorders of thyroid function (overweight, feeling heat, tides);
• Osteoporosis;
• Mental disorders (induced schizophreniform psychosis);
• The redness of the joints, pain in the extremities (psoriatic arthritis).

Separately, they must remain in the psoriatic arthritis origin. This disease (such as psoriasis is an aggressive course with the following symptoms:

• The redness of the joints;
• The local temperature increase (caused by the inflammation of the structure anatomical);
• Violation of the functional activity of the affected joint;
• The feeling of pressure, "tight glove," all of that psoriasis;
• Pain, aggravated at night and subsiding in the afternoon.

Specific manifestations depend on the type and stage of the pathological process.

The severity of the disease

There are three main degree. Criteria for their separation are the severity of the current diseases that cause process and the area of great development of the lesion.

• Easy psoriasis. The papules of psoriasis are isolated or absent. There is a character that is mild itching of the skin, body temperature normal, generally no symptoms. Format isolated areas of hyperemia of the skin with clear, smooth contours. On the surface of the dermis are affected by white coloration of the skin flakes resembles dandruff. The General area of lesions is less than 3% of the whole body;
• Moderate ringworm. The volume of an extensive growth of psoriatic changes are expressed and constitute about 3-10% of the body surface. Plaques multiple, delimited from one another, the clusters do not form. There is a slight hyperthermia with subfebrile values of the thermometer (around 37-37.5 degrees);
• Severe psoriasis is a psoriasis in a different way. The affected area of the skin for more than 10% of the body. The diameter of psoriatic plaques is several centimeters. Sections of the pathogenic process of multiple merge into a single complex. Pronounced redness, swelling of the dermis.

There is another method to determine the severity of the process in the so-called index PASI (PASI), psoriasis:

This is a multi-factor scale to take into account all the data in the system. It is regarded as the most accurate technique to determine the complexity of the flow.

The quality of life of patients

Ringworm of the specified type refers to a severe systemic diseases. As with any complex disease, zoster significantly reduces the quality of life of patients, as indicated by the data of numerous studies.

So, as has been said by the patients themselves, learn to live with the problem, however, have difficulties in a number of areas:

• In their professional activities. Psoriatic arthritis, the constant itching, and other factors that interfere with the normal physical work;
• In the domestic sphere. In especially difficult cases, patients not even able to care for themselves;
• In the field of leisure. The people affected are unable to participate in some kind of sport, experience psychological distress because of the unaesthetic appearance of the skin.

We must talk about the stigmatizing disease. Surrounding the fear of its contagiousness, which greatly affects the self-esteem of the patient. In addition to the physical discomfort and even mental notes. For obvious reasons, the private individuals, often fall into depression, looking for social isolation.

Therapies

How to cure psoriasis? Therapy must be comprehensive. First of all, we are talking about medicine effects on the body. Is assigned to the following groups of drugs:

• DZ-vitamin preparations. Considered to be quite safe, since they do not have serious side effects. Have a pronounced antiproliferative effect, the reduction of the rate of division of the cells of the skin. This includes: Minisan, Oksidevit, Aquadetrim;
• Retinoids. Dangerous drugs with serious side effects. However, they can be the answer to the question of how to cure psoriasis. Trade names: accutane, Acitretin, Soriathan;
• Suppressors of immunity. Neural, Methotrexate, Cyclosporine;
• Finally, the answer to the question "how to treat psoriasis developed" may lie in the use of corticosteroids: Prednisone, Dexamethasone, etc..

Also practiced methods of physiotherapy:

• UVF radiation;
• Ultrasound;
• Electrosleep.

Answers to the question of how to cure psoriasis there are many. To determine the tactics of therapy can be a doctor. There are many nuances, it all depends on the severity of the disease and its location.