Ointment of psoriasis - what is the most effective ointment for psoriasis?

People living with a diagnosis of "psoriasis" I know first-hand the amount depends on the right choice of the medication. This disease does not forgive errors in the treatment and the attitude of negligence to their health. An important role in the control of symptoms of the psoriasis to play a well-chosen external therapy and timely treatment. A key principle in the choice of patterns of treatment, especially in the early stages of psoriasis development, is the principle of "do no harm" treatment should not strike at the health of the skin, provoking the emergence of unintended consequences in the form of skin atrophy or syndrome. After all, the main goal of therapy is to lengthen rest periods and to the health of the skin without a sudden and painful relapses and exacerbations.

ointment of psoriasis

Hormonal ointments for psoriasis: cure or kill?

A common group of external agents for the treatment of psoriasis are ointments on the basis of special hormones. These substances have the property of suppressing the activity of the immune system, reducing inflammation. Therefore, in severe exacerbations of psoriasis steroid administered systemically as tablets or injections. However, this approach is fraught with serious side effects: therapy alters the hormonal balance of the body, and the withdrawal of drugs can lead to the malfunction of the endocrine systems and cardiovascular.

Topical steroids (external hormonal) are, in part, devoid of dangerous properties of system of drugs based on hormones: the effect is manifested only at the site of application. Its advantage is the rapidity of the action: a couple of minutes after the application, patients notice a decrease in pruritus, and in the next few days, it significantly reduced the redness of psoriatic plaques, stops their growth, and peeling.

Unfortunately, the side effects typical for steroids topical — and no less serious: because of the low immunity at the site of application, the skin becomes thinner and discolored, there is a risk of infection secondary. This, certainly, hinders the treatment. The most serious consequence of the use of steroids topical is the development of addiction. As a result, other products (even the topical steroids) already stopped to help, causing another, sometimes much more severe relapse after discontinuation of the drug. For this reason, the sale of topical steroids in Europe and the United States without a prescription is prohibited. Independent and uncontrolled use of these funds related to the category of powerful, unacceptable.

It is important to know! Addison's disease — a condition that develops due to prolonged medication of corticosteroids. In response to the hormonal therapy usually adrenal glands stop producing cortisol and other steroids, which is manifested by symptoms such as muscle weakness, loss of weight and appetite, decreased blood pressure, dehydration, heart palpitations and constant anxiety. In Addison disease, the doctors are not always able to restore the adrenal function, so that the patients life prescribed hormonal therapy.

Most of the funds on the basis of topical steroids is low cost and that are sold without prescription, so the cases of abuse of this type of psoriasis are common. In the meantime, dermatologists do not recommend the use of local steroids is extensive (more than 20% of the surface of the skin) areas of the lesions, and to apply these funds to the sensitive areas of the body, face, neck, skin folds and diaper rash. It is desirable to completely abandon the idea of using hormonal ointments and creams without prescription: it is able to reduce the effect of the primary treatment, damage to health and provoke an attack of severe exacerbation of psoriasis.

The most common hormonal creams and ointments are made on the basis of the following substances:

  • betamethasone;
  • hydrocortisone;
  • mometasone;
  • methylprednisolone;
  • triamcinolone;

Traditional non-hormonal ointments for the treatment of psoriasis: will not be worse, but better?

Given the serious side effects of hormone creams and ointments, many patients prefer to treat psoriasis with a less "aggressive" medication. Some of them are the heritage of folk medicine and traditional recipes of skin treatment, popular in the past.

The advantages of the traditional non-hormone treatments for psoriasis, should be attributed to its comparison with hormonal products of security, low cost and the lack of serious side effects. The disadvantages of the different (often low) degree of efficiency and, in some cases, the allergic reactions that develop in patients in the components of a medium.

signs of psoriasis
  • Naftalan, Ichthyol, dermatological, based ointment of tar — anti-inflammatory and antiseptic. However, some of them can't use in the progressive stage of psoriasis, and large areas of lesions, while others (for example, coal tar ointment) have a certain effect, so they are not recommended to be combined with phototherapy. In addition, prolonged use of these drugs increases the likelihood of developing a skin cancer. Traditional ointments have a strong smell and can stain clothes, therefore they are not very comfortable to use.
  • Special substances have anti-inflammatory and antimicrobial action, and cause increased exfoliation of the dead skin cells which accelerates the healing process of psoriatic plaques. Among the possible side effects — the risk of reactions inflammatory diseases, burning sensation and pigmentation of the environment of the health of the skin (stains the skin healthy and the hair in brown color).
  • Herbal (ointments and creams based on aloe, elecampane, celandine, sage, and other herbs) have anti-inflammatory and healing effects, prevent the development of infections of the skin. He participated in the treatment of psoriasis, complementing the effect of the primary treatment.
  • Moisturizers (creams and baby oil, cosmetics) are also auxiliary in the treatment of psoriasis and helps combat the dryness of the skin and the feeling of tightness of the skin. Used in combination with drugs to enhance the effect of the therapy.

Non-hormonal creams and ointments, with a pronounced therapeutic effect: clinically

Also worth noting is a group of non-hormonal medicines that the efficiency in the local treatment of psoriasis, has been confirmed in clinical trials. Unlike ointments and creams of the previous group, the mechanism of action of these drugs is studied in detail. They have an undeniable advantage over hormonal products in relationship with a greater safety profile. However, in the treatment of these assets should clearly follow the instructions for use and be aware of the possible side effects.

  • Pimecrolimus has high anti-inflammatory activity. However, be aware that in the case of bacteria or fungi on the skin of the application of funds on the basis of pimecrolimus is recommended only after the healing of the infection. Uncontrolled use of pimecrolimus may cause local immunosuppression in the skin (local suppression of the immune system), increasing the risk of joining a secondary infection in the affected areas of the skin. Therefore, in the united states, for example, pimecrolimus is recommended only as a drug "second-line" treatment, that is to say, only in the absence of the effect of other means of therapy. Pimecrolimus is prohibited for use by children up to two years.
  • The calcipotriol is a synthetic analogue of vitamin D3. Its action is based on increasing the level of calcium in the cells of the skin, normalizes the rhythm of your division and promotes the resorption of psoriatic plaques. Due to calcipotriol is hormonal remedy (which, after a series of biochemical reactions is converted into the active hormonal metabolite of calcium metabolism), there are a series of restrictions on their use. In particular, the calcipotriol does not apply if you lose more than 30% of the surface of the skin because of the risk of hypercalcemia. The latter can cause irregular heartbeat and muscle cramps. It is not advisable to apply a calcipotriol to the skin sensitive areas (face, neck, folds). Means on the basis of this active substance has age restrictions. Of calcipotriol also it is not suitable as auxiliary means in case of treatment of phototherapy, because under the action of UV light causes photosensitivity and leads to the development of skin burns.
  • The pyrithione zinc. Given the proven efficacy and safety of the treatment, the medications for the treatment of psoriasis based on this active substance can be attributed to the category of Gold said". Zinc is a organic and natural cure for the treatment of diseases of the skin. Its concentration in healthy human epithelium is approximately 20% of the total content in the body, and the deficit of this valuable metal is accompanied by various skin lesions and impaired wound healing. Drugs with the active participation of zinc (zinc pyrithione) have a set of specific properties (anti-inflammatory, antibacterial, antifungal), to help reduce the itching, the promotion and development of ceramides (lipids) in the skin, which leads to the restoration of its function as a barrier. Tools zinc pyrithione activate the so-called apoptosis (natural programmed death) pathologically altered cells of the skin and the cells of the inflammation, to activate the natural renewal of the cells of the skin, reducing the flaking and the elimination of the psoriatic plaques. Studies have shown that the active zinc has a comparable hormonal products efficacy and the good safety profile as is practically not absorbed from the skin, has no annoying and damaging effect.

Ointment or cream?

Many of these medications are produced in the form of an ointment and a cream. How to choose the most appropriate way?

  • Ointments are more dense and oily texture, which allows the drug to be a long time on the surface of the skin, especially if you put it under the bandage.
  • The cream has a texture more soft, more easy to apply and absorbs more quickly, so that it can be applied, leaving the skin open, not using the bandages and have no fear of staining your clothes or hands. In general, the cream has a pleasant smell that is also important for the daily use.
  • Unlike ointment, cream, to a lesser extent, an irritant, because it is the most suitable for application to the face, the bending of the joints, the areas with a high sensitivity. Also ointment is not suitable for application in humid areas of the skin affected with the liquid is high. The cream is in this sense more universal.
  • Traditionally, the ointment of psoriasis presents more extensive, however, this imbalance gradually disappears — the market appears more and more new dosage forms in the form of creams, gels, and aerosols are convenient to use and particularly suitable for application in inaccessible areas (for example, the scalp).
the treatment of psoriasis

Looking for a balance between price and quality

We will try to summarize the information in a table:

Group of drugs

The active ingredient

Action

Possible limitations and side effects

Hormonal creams and ointments

Betamethasone

Possess anti-inflammatory, anti-allergic (including anti-itching) and anti-edematous action. Hydrocortisone, methylprednisolone and other tools also have a certain action (overwhelming local immunity of the skin).

1. Not recommended for long-term use (more than 5 days) and often. 2. Can cause the development of complications:

  • the discoloration and metabolic disorders in the skin;
  • syndrome;
  • the immunosuppressive effect can lead to the accession of secondary infection to the skin.
  • Contraindicated:
  • for use in sensitive areas of the skin (face, neck, folds);
  • when large areas of the lesion (more than 30% of the skin).

Mometasone

Hydrocortisone

Glucocorticoid remedy

Methylprednisolone

Triamcinolone

Non-hormonal traditional media

  • Oil
  • Sulfur
  • Ichthyol
  • Fat
  • Tar

Possess anti-inflammatory and antiseptic.

  • They have a fairly low efficiency and no effect on bacterial and fungal agents (when joining a secondary infection of the skin).
  • Uncomfortable to apply (apply several times a day, often under the bandage, require prolonged treatment, stain clothes and have an unpleasant odor).
  • Can cause irritation and dryness of the skin, and allergic reactions.

The substance that causes the active exfoliation of dead cells from the surface of the skin:

  • dithranol
  • sulfur and salicylic acid

Cause increase exfoliation of the dead skin cells from the skin, have anti-inflammatory and antimicrobial action.

It can cause an inflammatory reaction, burning sensation and pigmentation of the environment of the health of the skin (stains the skin healthy and the hair in brown color).

Non-hormonal drugs

Pimecrolimus

It has anti-inflammatory activity.

  • Not recommended in case of bacterial or fungal infections of the skin.
  • Can cause local immunosuppression in the skin (reduction of the immunity and local).
  • Contraindicated in children up to two years.

Of calcipotriol

It is a synthetic analogue of vitamin D3, promotes the resorption of psoriatic plaques.

  • Not recommended:
  • to apply if you lose more than 30% of the surface of the skin because of the risk of hypercalcemia;
  • apply to sensitive skin areas (face, neck, folds, scalp);
  • combined with the method of phototherapy in relation to the risk of receiving skin burns.
  • Contraindicated for patients under the age of six.

Zinc pyrithione

Has a complex action:

  • anti-inflammatory;
  • antipruritic;
  • protection against infection;
  • the activation of the natural renewal of the cells of the epithelium to eliminate psoriatic plaques;
  • the restoration of the function of barrier of the skin.
  • It has a high safety profile.
  • Has No restrictions on the duration of use and field of application.
  • Has No side effects (except individual intolerance).
  • Approved for the use of children with a year.

Psoriasis is a chronic disease because every patient is important to find the best remedy, combining the high efficacy and low side effects (and, preferably, at a reasonable price). And remember: before you start using any tool, read the instructions, all the possible contraindications and side effects, and also be sure to consult with your doctor. This will help you to get the best results without injury.

ointment against psoriasis

Principles of psoriasis treatment is a key success factor. Remember that the sooner you begin to treat psoriasis, the less likely that you will never have to resort to "heavy artillery" hormonal means.